20 articles - From Friday May 26 2023 to Friday Jun 02 2023
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
| Pancreatology |
Predictive ability of pancreatic cyst fluid biomarkers: A systematic review and meta-analysis. Cyst fluid analysis can be a valuable tool in the characterization of pancreatic cysts, with relevant clinical implications. Our results support the use of DNA-based cyst fluid biomarkers in the multidisciplinary diagnostic work-up of pancreatic cysts. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
A randomized clinical trial comparing low-fat versus precision nutrition-based diets for weight loss: impact on glycemic variability and HbA1c. Personalized diet did not result in a greater reduction in GV or HbA1c in patients with prediabetes and moderately-controlled T2D, compared to a Standardized diet. Additional subgroup analyses may help to identify patients who are more likely to benefit from this personalized intervention. Clinicaltrials Gov identifier NCT03336411. |
How is online self-reported weight compared with image-captured weight? A comparative study using data from an online longitudinal study of young adults. This study demonstrates the method concordance of image-based collection methods with self-reported weight in online research. |
Multivitamin Supplementation Improves Memory in Older Adults: A Randomized Clinical Trial. Daily multivitamin supplementation, compared with placebo, improves memory in older adults. Multivitamin supplementation holds promise as a safe and accessible approach to maintaining cognitive health in older age. |
Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a HEEDS Workshop. This report details the discussions, key areas of agreement and future opportunities to prevent obesity. The attendees agreed that environmental obesogens are real, significant, and a contributor at some level to weight gain at the individual level and to the global obesity and metabolic disease pandemic at a societal level moreover, it is at least, in theory, remediable. |
| Inflamm Bowel Dis |
Bedside Intestinal Ultrasound Predicts Disease Severity and the Disease Distribution of Pediatric Patients With Inflammatory Bowel Disease: A Pilot Cross-sectional Study. Increasing BWT is associated with increasing endoscopic activity in pediatric IBD. Our study suggests that the optimal BWT cutoff value for detecting active disease may be less than that seen in adults. Additional pediatric studies are needed. |
Responsiveness to Vedolizumab Therapy in Ulcerative Colitis is Associated With Alterations in Immune Cell-Cell Communications. Overall, our results indicate that efforts to elucidate cell-cell communications among immune and nonimmune cell types may increase the mechanistic understanding of current and investigational therapies for IBD. |
| J Crohns Colitis |
A comparative evaluation of the measurement properties of three histological indices of mucosal healing in ulcerative colitis: Geboes Score, Robarts Histopathology Index, and Nancy Index. The GS, RHI, and NI are each capable of producing reliable and valid scores that are sensitive to changes in disease activity over time, in patients with moderately to severely active ulcerative colitis. While al three indices demonstrated relatively acceptable measurement properties, the GS and RHI performed better than the NI. |
Bacterial oncotraits rather than spatial organization are associated with dysplasia in ulcerative colitis. Biofilms are a hallmark of UC, however, because of their high prevalence a poor biomarker for dysplasia. In contrast, colibactin presence and FadA absence independently associate with dysplasia in UC and might therefore be valuable biomarkers for future risk stratification and intervention strategies. |
Impact of Holding Immunosuppressive Therapy in Patients with Inflammatory Bowel Disease Around mRNA COVID-19 Vaccine Administration on Humoral Immune Response and Development of COVID-19 Infection. We recommend continuing IBD medications while receiving mRNA COVID-19 vaccination without interruption. |
| Liver Transpl |
Geographic disparities in access to liver transplantation. We must simultaneously work at the national level to standardize and share patient data (including socioeconomic status and geographic social deprivation indices) to better understand the factors that contribute to geographic disparity. The complex interplay between organ distribution policy, referral patterns and variable waitlisting practices with the proportion of high MELD patients and differences in potential donor supply, must al be considered to create a national policy strategy to address the inequities in the system. |
Redo hepatic artery reconstruction for thrombosis without retransplantation in 1,355 adult living donor liver transplantations. In conclusion, the successful redo-reconstruction under careful selection criteria saved the graft without re-transplantation in 96.0% of the cases. Surgical revascularization should be preferentially considered for the management of HAT in ALDLT. |
| Pancreatology |
Promoter hypermethylation of SFRP1 as a prognostic and potentially predictive blood-based biomarker in patients with stage III or IV pancreatic ductal adenocarcinoma. Together with existing literature, results could indicate the value of cfDNA-measured phSFRP1 as a predictive biomarker of standard palliative chemotherapy in patients with metastatic PDAC. This could facilitate personalized treatment of patients with metastatic PDAC. |
Risk of pancreatic cancer after acute pancreatitis: A population-based matched cohort study. The risk of pancreatic cancer increases rapidly after acute pancreatitis diagnosis, gradually declines after 2 years, and remains elevated for up to 10 years. Further studies are needed to determine the long-term effects of acute pancreatitis on the risk of pancreatic cancer. |
Safety and efficacy of endoscopic ultrasound-guided radiofrequency ablation for pancreatic insulinoma: A single-center experience. Data from this case series suggest that EUS-RFA is a feasible and safe therapeutic approach for pancreatic insulinomas in patients unwilling or unable to undergo surgery with medium-term efficacy. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Am J Clin Nutr |
| Inflamm Bowel Dis |
misc publications eg case reports, tools of the trade, images of the month, etc…
| J Crohns Colitis |
| Liver Transpl |
Letters to the editors and authors’ replies